Computational Insights into Five- versus Six-Coordinate Iron Center in Ferrous Soybean Lipoxygenase
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Computational Insights into Five- versus Six-Coordinate Iron Center in Ferrous Soybean Lipoxygenase
Soybean lipoxygenase (SLO) serves as a prototype for fundamental understanding of hydrogen tunneling in enzymes. Its reactivity depends on the active site structure around a mononuclear, nonheme iron center. The available crystal structures indicate five-coordinate iron, while magnetic circular dichroism experiments suggest significant populations of both five-coordinate (5C) and six-coordinate...
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ژورنال
عنوان ژورنال: The Journal of Physical Chemistry Letters
سال: 2016
ISSN: 1948-7185
DOI: 10.1021/acs.jpclett.6b01626